13 February 2018

Have We All Suffered Too Much From an Over-Dose of Vitriol and B.S. Yet?

 Is anyone else exhausted from being profiled based on folks whose primary form of exercise appears to be jumping to conclusions; conclusions that lead to labeling people in ways that are in accordance with negative prejudices?  Is anyone else even more tired of the low-level harassment that occurs because of that exercise, and the retributive form it takes based on group prejudices from folks who are in positions which enable them to call on others to harass intended targets instead of doing it themselves?

There is a word for the problem (several in fact but I'll stay with one, for now):  "corruption".
Are there justified reasons for the corruption?  I say no, that corruption along with the attitudes and behaviors it spawns, altogether, are always malicious and unwarranted. 

Given the numerous decades in which I have been observing and experiencing these attitudes and behaviors plus their negatively intended destructive consequences, I have found there are a few favorites supposed as "reasons" by unethical people with control issues.  Their negative profiling of others is based on their own willingness to jump to unfounded conclusions, as well as the willingness of those exposed to their censuring efforts that target third-parties.  A primary favorite "reason" is dissatisfaction with anyone who is not willing to submit to pressure to convert politically,  religiously, or these days socially (whatever might be the nebulous meaning attached to socially, although it ordinarily seems to be associated with the desire to dictate belief in an ideology which encompasses all the components of an entire belief system).

The retributive intent of those trying to define unwilling converts as having polar opposite perspectives, results in categorizing people as problems, thus threats who they believe deserve to be harassed into compliance.  However, the folks embracing such violent attitudes who are creating the problems, would never be physically violent themselves.  A large part of the work they actually do is in finding ways to manipulate others into doing their dirty work of all types - either as dupes, or through cooperation.

Most who have done the work of knowing themselves so they can continue successfully working to make themselves into who they want to be and to become throughout their lives, of course for the value they can be to others because of doing so, are unwilling to consent to anyone else defining the obvious about them, or defining what is assumed though unknown (e.g. beliefs, opinions, perspectives).  However, unethical people are simply not happy that others are unwilling to buy hook, line, and sinker into whatever political ideology or religion they are trying to peddle, so engage in frenzies of malicious "defining" of those who they consider to be resistant to buying.  Many problems would not develop if folks would not be so quick to buy into what might sound good without first doing their own research.  When we do not do this we can easily become dupes for the malicious among us who link their own success to the amount of success they have in convincing others to buy into the beliefs they are pushing on us, whether they are beliefs about groups of people or individuals.

Fact is I feel no obligation whatsoever, myself, to be forced by anyone else to formulate an opinion about something for which I have not acquired enough knowledge to formulate an opinion through my own efforts. I doubt and question, repeatedly, until I have found enough factual trustworthy documented facts to alleviated doubt, then formulate an opinion.  And even when I do take a stand, I remain flexible enough to adjust it based on whatever new factual information may become pertinent. In fact it is a process of applying the scientific method to daily life choices - comparable, sometimes, to sitting on the fence.

Winslow Homer 1874
Sitting on the fence is an art which some have not mastered.  It includes choosing one's fences wisely.  I learned, long ago, to be comfortable sitting on the fence alone, and with others, as long as needed.  And I have chosen to become intolerant of those trying to push me off the fence to satisfy some perverse competitive self-interest need by which they are motivated to try to compete with and control others. I can not count the times I have been an intended victim of someone’s competitive ambitious attitude, never knowing there was a competition, or why.  It is like an undeclared war of which one is unaware. Can it be attributed to gaslighting narcissism?  Perhaps.  But when it can be defined as a situation that is pervasive throughout the political landscape, or within organizations, groups, or families . . .  it becomes systemic dysfunction and failure.

Who would foolishly imagine other people do not have enough survival issues of their own around which it is necessary to be able to schedule their undivided attention (along with the survival issues of those in their lives they are able to willingly assist, when needed)?  What type of person imagines we are able or willing to accommodate and give priority to the competitive personal-interest issues of their demands?  But when we do not do so we are then defined as threats by the corrupt among us whose demands we do not meet.  The ongoing low-level retributive harassment which targets those who do not cooperate with such demands, is intended to redirect a "threat's" time, effort, and energy to the self-interest needs of those making demands - those whose control issues motivate their own successes which they want to believe are dependent on requiring others to pay for those successes with unwarranted  blood, sweat, and tears demanded of them.

I have put in more than my own share of time being swindled by the destructive attitudes of other people, both as a child and as an adult, attitudes which I have never chosen to also accommodate as part of who I am.  That is partly because a number of people have unknowingly served in the position of being cautionary tales in my life.  No doubt I have been in the same service to other folks, though I ordinarily know when that is the case.  Fact is a majority of  my time, effort, and energy has too often been abused because of it having been redirected to meet self-serving  whims of others.  Without doubt too many have been and/or continue to be plagued by such problems in over abundance.  But, throughout my entire adult life I have not been willing to remain silent about them, particularly systemic problems. No one should be silent, in my opinion.  But why some are is understandable.  Speaking up instead of remaining silent is often  perceived by the unethical and corrupt as a threat, thus an invitation for ongoing retributive harassment.  And that is exactly why some choose to remain silent.  It is not easy to be a front-line boat-rocker because of the possibility of falling into the deep.  When that happens it can be difficult to extricate oneself when unexpectedly sinking . . . or swimming . . . alone.

When I speak of not remaining silent I am not speaking merely of belly-aching, grousing, and complaining about annoying inconveniences and irritations, though we find ourselves doing that from time to time. I am referring to speaking up about ongoing prevaricating, cheating, truth-twisting, the all around bamboozling that is intended to be maliciously misleading and happens to be at the foundation of most systemic problems which have developed and will continue to exist and further develop unless addressed, not only in the personal lives of people, but throughout nations. That unaddressed problems create turmoil and chaos too often leading to violence, death, and destruction, including self-destruction, is abundantly clear.  I am suggesting that speaking up means making efforts to effectively handle problems based on requests all are entitled to make and expect to have honored, for compliance with enforcement of standards, rules, laws, ordinances; requests which are not necessarily accomplished through the creating of public drama unless it is well-timed, supplementally, to draw attention to issues in need of more public attention and understanding.

My own attitudes and experiences are not, and never have been in accordance with what is statistically projected on all of us, based on being categorized by those who have nothing better to do with their lives than put limits on other people in that way.  Few individuals can be easily fit into such ready-made statistical and psychological profiles.

I have become weary of coming across as a problem every time I choose to speak up about unnecessary, ill-intended low-level harassment by folks who create chaos through pulling the strings of the puppets at their beck and call to do their harassing; puppets who rarely completely know how they are being used, beyond being lead to believe targeted individuals are creating problems for which they themselves are unjustly being blamed.  However, long ago I observed that the majority of created problems are due to intentional failure to communicate precisely, which allows excessive space for assuming, and jumping to unwarranted conclusions by those inclined to do so.  Refusing to communicate, and refusing to make an effort to communicate precisely, are favorite weapons in the arsenal of those who choose to be corrupt and unethical at cost to everyone else.

Is there a solution?  I think there are many, actually.  Whether in doubt of others, or not, it is never wrong to have enough respect for others to kindly ask folks, directly, who they are, what they believe and why, then take the time required to allow oneself to be informed by the ways in which they respond.  Most people are capable of being articulate enough to comment objectively about themselves and are willing to do so, including, when necessary, defending themselves against whatever objections others may express about differing viewpoints, and/or what does not seem to them to be clearly communicated.  Having the courage to speak with people, directly, instead of making assumptions about them based on what others have said, is an effective way to solve most problems caused by others, given that we are not always aware of the foundational roots of many problems which have intentionally been caused by third-parties (or fourth, fifth, sixth . . . ).  The opportunity for objective self definition is ordinarily welcomed by most because it is certainly better than the alternative of others imagining they have the right to define us; and better than the alternative of some who believe others are more entitled to define us than we are to define ourselves.

Succinctly? Well, folksy, down-home traditional wisdom has always taught us that unless it comes from the horse's mouth, it is not advisable to eagerly buy into it.  Ask.  Asking is always the best policy.  It is one reason we were blessed with entire languages full of words and the ability to communicate clearly with them.

06 February 2018

The Surprisingly Extensive Mammalian Endo-Cannabinoid System and CBD

There is value in cannabidiol (CBD) found in all types of hemp, including Marijuana with its psychoactive constituent THC (tetrahydrocannabinol).  CBD is found throughout the seeds, stalk, and flowers of cannabis plants where it occurs in more significant quantities than in other known sources of cannabidiol. It is extracted in the form of cannabis oil.

CBD is available without psychotropic effects and no matter what type of cannabis it comes from, marijuana or non-psychoactive hemp, it has often been referred to as "medical marijuana".

“Hemp”, unless otherwise stated, will here refer to plain old weedy non-psychactive industrial hemp, the plant long used for rope making, and today used for making fabric and paper, among its many other uses, which also includes use of the seeds for nutritional value. Industrial hemp grows like a weed thus is of high value for its easily renewable sustainability. 

I am not addressing the subject for the purpose of discussing the hot-button political issue of federal legalization of marijuana.  However, I am commenting on the hot-button political issue associated with the value of CBD in holistic integrative healing and questioning why it is being maligned by the mainstream pharmaceutical-centric medical industry.

The fact that cannabinoid  (CBD) is used by the cannabinoid receptors in the body to keep us healthy, certainly does raise questions about why not only marijuana but also hemp has been so maligned for so long.  And it absolutely raises questions about maligning hemp from which CBD can be extracted for the purposes of healing thus avoiding the still unresolved hot button political issue of the THC in marijuana, even though it is removed from the CBD that is extracted from marijuana to be used as "medical marijuana".

It is fairly well known that marijuana and hemp are different varieties of the same genus Cannabis sativa.  A little more botanical background, not as well know, is that the family Cannabaceae of which Cannabis is part, also includes Hops and Hackberries trees and is of the order Rosales which is comprised of nine families, including the hemp, Russian olive, mulberry, buckthorn, rose, elm and nettle families.  In other words Cannabis and Roses are cousins.

I want to point out for those who are not aware, that the growing of hemp as a controlled substance has been in effect since colonial days.  I discovered this way back when, while doing genealogical research of a gateway ancestor to Virginia who was documented as having had a license to grow hemp.  At the time the maritime industry, for one, was hugely reliant on hemp for the making of rope.  It was a profitable  crop.

However, the fact that the growing of hemp was regulated, then, apparently says something about the difficulty of distinguishing between marijuana and hemp while not trusting growers to grow industrial hemp unless it could be regulated. For example, is the cannabis image, up above, marijuana or hemp?

We might deduce from this, accurately or not, that Colonial regulation suggests government folks could test the hemp to determine the veracity of a grower’s claim that it was non-psychactive i.e. not marijuana with it’s pesky THC.   It is interesting to imagine the nature of testing by representatives of the crown . . .

Let me simply say there is a huge body of research about the value of hemp CBD in healing.  To that end the use and availability - affordable availability - of natural, not synthetic CBD - is all about being healthy without having to fight government and health care professionals for the right to be healthy in the most effective least damaging ways.  CBD is not the only issue in that battle of course.

What we know in 2018 is “Cannabinoid receptors are found in nearly every tissue of the body and brain. These receptors are part of the mammalian endocannabinoid system, which includes the brain and both the central and peripheral nervous systems. The receptors respond to the components found in cannabis, acting separately but holistically with the body’s other receptor systems. Because there are so many of these receptors, cannabis may help with a large number of conditions.”  This from a “Cannabis for Cats” article at Animal Wellness website, CBD being advised for pets at times, for the same reason it is advised for people and other mammals, because cannabinoid receptors are part of the mammalian endocannabinoid system. 

Let me say that one more time:  cannabinoid receptors are part of the mammalian endocannabinoid system, an astounding discovery from 30 years ago.  It should be common knowledge by now, but it is apparently the type of news not deemed worthy of being offered, repetitively, in the way other topics are, like crime, and sordid  reports of scandalous behavior.

Even more astounding about the Endo-Cannabinoid System is "there are more receptors for CBD in our body than any other kind of receptor.  So the Endo-Cannabinoid System is truly the largest network of its kind throughout our entire physiology." This is a comment by Asher Milgrom, PhD, CEO & Chief Scientist, AMA Regenerative Medicine. in the video, “The Inside Story of Cannabidiol - What are the Benefits of CBD?", where he addresses the physiological effects of CBD.  The process of the importance of homeostasis is explained with reference of course to CBD, since it is the Endo-Cannabinoid System being addressed.  Again, that is the largest network of its kind throughout our entire physiology, but apparently not the type of news deemed worthy of being offered, repetitively.  As Dad used to say when suggesting the advantages of thinking deeply in a big picture cause and effect way, "put that in your pipe and smoke it!"

Though the model of a mobile Asher Milgrom uses in the video is simplistic, it is useful in clearly illustrating the level at which CBD works in the integrative medicine model of holistic healing; contrasted to treating isolated symptoms with pharmaceuticals which leads to problems from isolated treatment, then more isolated treatment of symptoms with more pharmaceuticals . . . ad infinitum to damaging proportions because of numerous noxious pharmaceuticals.  There are natural means available that are non-toxic.

Even for folks who already know and understand the physiological processes of homeostasis Milgrom describes, the nearly 22 minute video is worth watching for the way he describes the value of CBD in the process of homeostasis.  It maintains and establishes balance in the Endo-Cannabinoid System.  He contrasts the holistic systemic effects of CBD with the way combinations of pharmaceutical drugs are used to treat individual bodily symptoms and the problems that present from doing so.

To be fair, many allopathic physicians are coming around to educating themselves and getting themselves educated about the holistic approach to treatment, thus they are more willing to work with integrative physicians (or become integrative physicians, themselves) so that natural treatment can be used  - along with pharmaceutical treatment to make it more effective when pharmaceutical treatment is needed.

In the video Asher Milgrom attributes a 1992 discovery of the Endo-Cannabinoid System to Dr. Rafael Mechoulam of Hebrew University.  More about the history of the discovery of the Endo-Cannabinoid System can be found at this link: The Endocannabinoid System: A History of Endocannabinoids and Cannabis.  There are undoubtedly many other sources about the history of the discovery, the researchers, and their peer-reviewed research.  Project CBD is mentioned in the video as a resource.

This article “CBD is Not Just Another Nutritional Supplement” may not be an exact transcript of the video, but is close to it.  And yes, at the end of both the video and the article a business and it's products are discussed, briefly.  But it does not devalue the usefulness of the information presented - at least to anyone concerned with the need for healing and maintaining of optimum health

Research seems to have started earlier than 1992 because "In 1988, the first cannabinoid receptor was found in the brain of a rat. Initially found by Allyn Howlett and William Devane these cannabinoid receptors turned out to be plentiful in the brain – more so than any other neurotransmitter receptor."  This is when the prevalence of cannabinoid receptors was discovered some 30 years ago.  It is stated that Dr. Rafael Mechoulam discovered the body produces some amount of CBDs.  However, these are not in the quantities the prevalence of receptors indicates is designed to be acquired only from internal production.  So again the question arises of why the use of CBD has become a politicized issue given the fact that the mammalian body has a prevalence of receptors.  One might be tempted to imagine that with the prevalence of receptors in the body, qood quality unpolluted CBD is needed by the body to maintain health.

Consider the value of CBD to mammalian healing and maintaining of health.

Addendum 22 June 2020

This TED Talk video, Demystifying the endocannabinoid system, is a good companion video to Dr. Milgrom's video.  In it Dr. Ruth Ross provides additional information about the Endocannabionoid system.  Near the end she describes what happens in the brain when tetrahydrocannabinol is introduced i.e. THC (the high in cannabis, and one of the primary ingredients of cannabis).  

Milgrom's video is presenting evidence of the medicinal value of CBD (i.e. medical marijuana which is cannabis without the THC and/or with the THC removed) and how it benefits the body through the endocannabionoid receptors, while Ross' later video suggests that cannabis with the THC present (recreational cannabis) is not necessarily of medicinal value. 

Together they provide a more comprehensive insight into, and understanding of the amazing and  extensive mammalian  endocannabionoid system and its purposes.